abstract：:Radiocontrast exposure has now become an important cause of iatrogenic acute kidney injury (AKI) in hospitalized patients due to an increase in the number of diagnostic and interventional procedures done. Gadolinium, a well-known paramagnetic contrast agent used primarily for magnetic resonance imaging (MRI), has attr...

journal_title：Clinical nephrology

authors： Badero OJ,Schlanger L,Rizk D

更新日期：2008-12-01 00:00:00

abstract：BACKGROUND:The efficacy of lanthanum carbonate as a phosphate binder for the treatment of hyperphosphatemia has been reported, but not from a double-blind, comparator-controlled comparative study. METHODS:The safety and efficacy of lanthanum carbonate and calcium carbonate on serum phosphate and calcium levels in Japa...

journal_title：Clinical nephrology

authors： Shigematsu T,Lanthanum Carbonate Group.

更新日期：2008-11-01 00:00:00

abstract：:We report a second case of mesangial IgG glomerulonephritis recurrence after kidney allograft transplantation. Mesangial IgG glomerulonephritis is considered a distinct glomerulonephritis. To date, only 1 recurrence after transplantation has been reported. In the present case, recurrence occurred 3 months after transp...

journal_title：Clinical nephrology

authors： Jourde-Chiche N,Moal V,Daniel L,Purgus R,Legis T Jr,Vacher-Coponat H,Moussi-Frances J,Berland Y

更新日期：2008-10-01 00:00:00

abstract：BACKGROUND:Bariatric surgery achieves long-term weight loss in obese adults with improvement of diabetes and hypertension. Little is known about the effect of this weight loss on renal parameters. METHODS:We performed a retrospective study of 94 obese adults who had Roux-en-Y gastric bypass surgery with a mean 12-mont...

journal_title：Clinical nephrology

authors： Agrawal V,Khan I,Rai B,Krause KR,Chengelis DL,Zalesin KC,Rocher LL,McCullough PA

更新日期：2008-09-01 00:00:00

abstract：:A 72-year-old female who was admitted to our urology clinic with painless intermittent macroscopic hematuria existing for 3 months with no other voiding symptom was diagnosed with left pyelovenous fistula. Although a rare condition, pyelovenous fistula should be kept in mind when the cause of macroscopic hematuria can...

journal_title：Clinical nephrology

authors： Demir O,Ozdemir I,Bozkurt O,Seçil M,Esen A

更新日期：2008-09-01 00:00:00

abstract：BACKGROUND:Impairment of nitric oxide generation caused by gene polymorphism is considered as a major factor in the deterioration of progressive renal disease, including diabetic nephropathy and hypertension. The aim of the present study was to examine the Glu298Asp polymorphism of endothelial nitric oxide synthase (eN...

journal_title：Clinical nephrology

authors： Thaha M,Pranawa,Yogiantoro M,Sutjipto,Sunarjo,Tanimoto M,Gohda T,Tomino Y

更新日期：2008-08-01 00:00:00

abstract：:Nephropathies associated with thymoma or myasthenia gravis (MG) have rarely been observed. Furthermore, among the renal pathology of patients presenting with thymic and renal disease, focal segmental glomerulonephritis (FSGS) is the uncommon type. Herein, we report a case of a 50-year-old woman who suffered from intra...

journal_title：Clinical nephrology

authors： Chung S,Park CW,Song J,Kim JA,Shin SJ,Chang YS

更新日期：2008-07-01 00:00:00

abstract：:A 63-year-old man with systemic lupus erythematosus developed tubular proteinuria. All subclasses of serum IgG increased, and the largest IgG subclass increase was IgG4. A renal biopsy showed lupus nephritis (Class II) with severe tubulointerstitial nephritis (so-called predominant tubulointerstitial lupus nephritis, ...

journal_title：Clinical nephrology

authors： Omokawa A,Wakui H,Okuyama S,Togashi M,Ohtani H,Komatsuda A,Ichinohasama R,Sawada K

更新日期：2008-06-01 00:00:00

abstract：:An association between gadolinium-containing contrast and the development of nephrogenic systemic fibrosis (NSF) has been increasingly recognized. For patients receiving hemodialysis (HD) who are exposed to gadolinium, the Federal Drug Administration (FDA) recommends HD to remove this contrast agent in order to minimi...

journal_title：Clinical nephrology

authors： Murashima M,Drott HR,Carlow D,Shaw LM,Milone M,Bachman M,Tsai DE,Yang SL,Bloom RD

更新日期：2008-05-01 00:00:00

abstract：PURPOSE:Idiopathic retroperitoneal fibrosis (IRPF) is an unusual progressive illness for which consistent therapeutic recommendations have not been devised. The present report describes a collaborative nephrology and urology approach to distinguish IRPF from secondary disease and then combine necessary acute surgical o...

journal_title：Clinical nephrology

authors： Swartz RD,Lake AM,Roberts WW,Faerber GJ,Wolf JS Jr

更新日期：2008-04-01 00:00:00

abstract：:We report the case of a 63-year-old male patient on long-term hemodialysis who suffered two consecutive episodes of persistent hepatitis C virus infection with different genotypes and was successfully treated with pegylated IFN-alpha monotherapy each time. ...

journal_title：Clinical nephrology

authors： Lederer S,Zachoval R,Hasholzner U,Schiffl H

更新日期：2008-04-01 00:00:00

abstract：:Antibiotic-impregnated cement is used frequently in revision procedures of infected total hip and knee arthroplasties. Local antibiotic treatment is as effective as the use of systemic antibiotics. The purpose of such treatment is to provide high tissue concentrations of antibiotics and minimize systemic toxicity, esp...

journal_title：Clinical nephrology

authors： Dovas S,Liakopoulos V,Papatheodorou L,Chronopoulou I,Papavasiliou V,Atmatzidis E,Giannopoulou M,Eleftheriadis T,Simopoulou T,Karachalios T,Stefanidis I

更新日期：2008-03-01 00:00:00

abstract：:While an arteriovenous fistula is the best available form of hemodialysis access, a significant number of fistulae never mature to support dialysis (early failure) or fail after successful use (late failure). Venous stenosis and the presence of accessory veins are the two main causes of early failure. Recent data have...

journal_title：Clinical nephrology

authors： Mercado C,Salman L,Krishnamurthy G,Choi K,Artikov S,Thomas I,Merrill D,Asif A

更新日期：2008-02-01 00:00:00

abstract：OBJECTIVE:The purpose of this review was to examine potential barriers to adulthood transition for children and adolescents with chronic kidney disease (CKD). RESULTS:The literature was reviewed in regards to medical, neuropsychological, psychiatric and psychosocial barriers that may impede successful transition. Adul...

journal_title：Clinical nephrology

authors： Icard PF,Hower SJ,Kuchenreuther AR,Hooper SR,Gipson DS

更新日期：2008-01-01 00:00:00

abstract：AIMS:In this study, dose-response of the serum potassium-lowering effect of a calcium polystyrene sulfonate (PS) preparation was investigated. Changes in the serum potassium level were also examined with or without application of a RAAS inhibitor, which is said to increase the serum potassium level. SUBJECTS AND METHO...

journal_title：Clinical nephrology

authors： Tomino Y,Yamazaki T,Shou I,Tsuge T,Satake K,Takeda Y,Ohtani A,Nishitani T,Kurusu A,Hamada C,Horikoshi S,Maeda K,Tanaka Y,Fukuda H,Wakabayashi M,Seto T

更新日期：2007-12-01 00:00:00

abstract：AIMS:Unfortunately, clinicians are diagnosing a growing number of patients on hemodialysis (HD) with insulin-resistant, Type 2 diabetes in Japan. While alpha-glucosidase inhibitors (alpha-GI) such as oral antidiabetic agents are indicated for Japanese diabetics on HD, pioglitazone and other PPARgamma agonists are now c...

journal_title：Clinical nephrology

authors： Abe M,Kikuchi F,Kaizu K,Matsumoto K

更新日期：2007-11-01 00:00:00

abstract：AIM:The aim of our study was the long-term evolution of hepatitis B immunity and the titers of antibodies against the surface antigen (anti-HBs) acquired either naturally or after vaccination in hemodialysis (HD) patients with no history of hepatitis C virus (HCV) infection. METHODS:36 HD patients were vaccinated with...

journal_title：Clinical nephrology

authors： Tsouchnikas I,Dounousi E,Xanthopoulou K,Papakonstantinou S,Thomoglou V,Tsakiris D

更新日期：2007-10-01 00:00:00

abstract：:Multicentric Castleman disease is a systemic lymphoproliferative disease with incomplete understood etiology. The various renal complications of this disease may include minimal change disease, mesangial proliferative glomerulonephritis, membranous glomerulonephritis and nephrotic syndrome, caused by secondary amyloid...

journal_title：Clinical nephrology

authors： Ogita M,Hoshino J,Sogawa Y,Sawa N,Katori H,Takemoto F,Ubara Y,Hara S,Miyakoshi S,Takaichi K

更新日期：2007-09-01 00:00:00

abstract：:Antineutrophil cytoplasmic antibody-(ANCA) associated glomerulonephritis usually shows histopathologic features of pauciimmune crescentic glomerulonephritis and occurs late in life. We report a 14-year-old Japanese girl presenting with proteinuria, hematuria and mildly elevated serum creatinine. A renal biopsy specime...

journal_title：Clinical nephrology

authors： Jimbo R,Ubara Y,Tagami T,Higa Y,Suwabe T,Nakanishi S,Sogawa Y,Nomura K,Kadoguchi H,Hoshino J,Sawa N,Katori H,Takemoto F,Hara S,Hara S,Ohashi K,Takaichi K

更新日期：2007-08-01 00:00:00

abstract：AIMS:This 1-year double-blind, placebo-controlled, multicenter study evaluated the long-term safety and efficacy of cinacalcet for the treatment of secondary hyperparathyroidism in patients receiving hemodialysis. METHOD:Patients were randomly assigned in a 1:1 ratio to cinacalcet or control treatment groups. The init...

journal_title：Clinical nephrology

authors： Sterrett JR,Strom J,Stummvoll HK,Bahner U,Disney A,Soroka SD,Corpier C,Arruda JA,Schwanauer LE,Klassen PS,Olson KA,Block GA

更新日期：2007-07-01 00:00:00

abstract：BACKGROUND:Overall and cardiovascular mortality are significantly higher in hemodialysis patients with elevated C-reactive protein (CRP). The aim of this study was to determine whether CRP is a marker of overall and cardiovascular morbidity in chronic kidney disease (CKD) 3-5 patients. METHODS:90 chronic kidney diseas...

journal_title：Clinical nephrology

authors： Soriano S,González L,Martín-Malo A,Rodríguez M,Aljama P

更新日期：2007-06-01 00:00:00

abstract：AIM:This study was designed to assess the potential of the continuous erythropoietin receptor activator (C.E.R.A.) to correct anemia at extended administration intervals in erythropoiesis-stimulating agent-naīve patients with chronic kidney disease (CKD) not on dialysis and to determine its optimal starting dose. METH...

journal_title：Clinical nephrology

authors： Provenzano R,Besarab A,Macdougall IC,Ellison DH,Maxwell AP,Sulowicz W,Klinger M,Rutkowski B,Correa-Rotter R,Dougherty FC,BA 16528 Study Investigators.

更新日期：2007-05-01 00:00:00

abstract：:Smoking in young men may trigger anti-GBM disease manifesting with hemoptysis. We present a male adolescent in whom hemoptysis was mistaken to be a sign of airway infection for several months and who later on underwent an unusual antibody-negative relapse. The 16-year-old patient had a history of smoking and therapy-r...

journal_title：Clinical nephrology

authors： Benz K,Amann K,Dittrich K,Hugo C,Schnur K,Dötsch J

更新日期：2007-04-01 00:00:00

abstract：BACKGROUND:Chronic allograft nephropathy (CAN) is characterized by a progressive deterioration of renal function with various degrees ofproteinuria. Currently, there is no effective treatment despite the introduction of new generations of immunosuppressants. Pentoxifylline (PTX) is a phosphodiesterase inhibitor that po...

journal_title：Clinical nephrology

authors： Shu KH,Wu MJ,Chen CH,Cheng CH,Lian JD,Lu YS

更新日期：2007-03-01 00:00:00

abstract：:We report the case of a 42-year-old man who developed biopsy-confirmed acute interstitial nephritis (AIN) after cocaine sniffing. He required a few hemodialysis sessions but fully recovered within 3 weeks after cocaine withdrawal and a short course of corticosteroids. AIN should be recognized as a potential cause of a...

journal_title：Clinical nephrology

authors： Decelle L,Cosyns JP,Georges B,Jadoul M,Lefebvre C

更新日期：2007-02-01 00:00:00

abstract：:The pituitary gland can be involved in a variety of medical conditions, including metastatic tumors. Metastases to the pituitary gland, although absolutely rare, more commonly affect the posterior pituitary lobe and so frequently present with diabetes insipidus. We report on a 48-year-old male heavy smoker patient suf...

journal_title：Clinical nephrology

authors： Granata A,Viola G,Privitera C,Romeo G,Cacciaguerra S,Gaeta M,Sicurezza E,Figuera M

更新日期：2007-01-01 00:00:00

abstract：BACKGROUND:IgA nephropathy is the most common glomerulonephritis in the world. Thrombotic microangiopathy occurs in a number of clinical settings, including but not limited to thrombotic thrombocytopenic purpura/hemolytic uremic syndrome, malignant hypertension, anti-phospholipid antibody syndrome and radiation nephrop...

journal_title：Clinical nephrology

authors： Chang A,Kowalewska J,Smith KD,Nicosia RF,Alpers CE

更新日期：2006-12-01 00:00:00

abstract：:Aminoglycoside nephrotoxicity is a well-known clinical entity that complicates the course of infectious diseases treated under this antibiotic regime. Recently, a new administration form of tobramycin, inhaled tobramycin (TOBI), has been approved to improve the antibacterial activity and reduce nephrotoxicity. We desc...

journal_title：Clinical nephrology

authors： Izquierdo MJ,Gomez-Alamillo C,Ortiz F,Calabia ER,Ruiz JC,de Francisco AL,Arias M

更新日期：2006-12-01 00:00:00

abstract：BACKGROUND:Increased serum levels of S100A12, a proinflammatory protein secreted by activated neutrophils, have recently been shown in patients with active inflammatory diseases, such as rheumatoid arthritis and Kawasaki disease. In this study, we investigated serum levels of S100A 12 in patients with small-vessel vasc...

journal_title：Clinical nephrology

authors： Komatsuda A,Ohtani H,Wakui H,Chyzh KA,Hatakeyama T,Iwamoto K,Maki N,Kimura T,Hitomi J,Sawada K

更新日期：2006-11-01 00:00:00

abstract：:Hemodialysis patients develop metabolic acidosis due to their impaired excretion of daily produced protons (H+). The following report will show a rare case of severe metabolic alkalosis (predialysis pH 7.52, base excess (BE) +17) in a hemodialysis woman caused by self-provoked upper gastrointestinal H+ losses based on...

journal_title：Clinical nephrology

authors： Kirsch BM,Sunder-Plassmann G,Schwarz C

更新日期：2006-11-01 00:00:00

abstract：AIMS:We previously reported 2 hemodialysis (HD) patients with recurrent infections and selective immunoglobulin A deficiency (IgAD). We further demonstrated that serum IgA levels were lower and the prevalence of IgAD was higher in uremic patients. The exact mechanisms of IgAD in uremic patients largely remained unclear...

journal_title：Clinical nephrology

authors： Kuo MC,Chang JM,Tsai JC,Chen HC,Tsai WC,Lai YH,Hwang SJ

更新日期：2006-10-01 00:00:00

abstract：:Cystinosis is a rare metabolic disorder characterized by lysosomal cystine accumulation leading to multi-organ damage, with kidneys being clinically first affected. Longer survival of cystinosis patients due to successful renal replacement therapy, revealed previously unknown extra-renal symptoms of cystinosis, genera...

journal_title：Clinical nephrology

authors： Edens MA,van Son WJ,de Greef MH,Levtchenko EN,Blijham T,Wijkstra PJ

更新日期：2006-10-01 00:00:00

abstract：AIMS:C-reactive protein (CRP) is a component of the acute-phase reaction to inflammation, severe tissue injury, and infection. Investigations have shown that CRP concentration is highly increased in the urine during acute renal graft dysfunction and, therefore, may affect tubular cell metabolism. Nevertheless, no data ...

journal_title：Clinical nephrology

authors： Baer PC,Gauer S,Wegner B,Schubert R,Geiger H

更新日期：2006-09-01 00:00:00

abstract：:We report a case of a relapse of Henoch-Schönlein Purpura (HSP) associated with intake of paracetamol (also known as acetaminophene) and codeine. A 69-year-old man presented with fever, gross hematuria, acute renal failure, palpable purpuric skin rash over the legs, feet and arms, arthralgias and abdominal discomfort....

journal_title：Clinical nephrology

authors： Santoro D,Stella M,Castellino S

更新日期：2006-08-01 00:00:00

abstract：AIMS:Diabetes is the leading cause of chronic kidney disease (CKD) in the United States, and cardiac disease is the primary cause of death in patients with CKD and diabetes. The Prevalence of Anemia in Early Renal Insufficiency (PAERI) study evaluated the prevalence of anemia and associated comorbidities in a community...

journal_title：Clinical nephrology

authors： Lorber D,Reddan D

更新日期：2006-07-01 00:00:00

abstract：:Renal vein thrombosis (RV Thromb) is a serious complication ofnephrotic syndrome. Anticoagulation is usually recommended as the treatment of choice. This study reports 3 nephrotic patients diagnosed to have RVThromb combined with thromboembolic events. Low-molecular weight heparin (LMWHep) was given subcutaneously eve...

journal_title：Clinical nephrology

authors： Wu CH,Ko SF,Lee CH,Cheng BC,Hsu KT,Chen JB,Chien YS,Yang CC,Huang MC,Chuang FR

更新日期：2006-06-01 00:00:00

abstract：AIMS:Antineutrophil cytoplasmic antibodies (ANCA) are detected in most patients with crescentic glomerulonephritis and necrotizing small vessel vasculitis. ANCA cause renal inflammation and proliferation. Apoptosis is necessary for resolution of inflammation. We studied apoptosis, apoptosis-regulating proteins, prolife...

journal_title：Clinical nephrology

authors： Kettritz R,Wilke S,von Vietinghoff S,Luft F,Schneider W

更新日期：2006-05-01 00:00:00

abstract：:Hypouricemia is a common disorder in the general population. Herein, renal hypouricemia caused by human urate transporter 1 (hURAT1) gene mutations in a Japanese patient with intellectual disability is reported. She had compound heterozygous mutations in this gene (W258X and IVS2+1G>A), nevertheless, she showed no cli...

journal_title：Clinical nephrology

authors： Inazu T

更新日期：2006-05-01 00:00:00

abstract：:We report the case of a patient with uremic pleuropericarditis who showed a marked improvement following corticosteroid therapy. A 66-year-old man who had been on hemodialysis therapy for 13 years was admitted to our hospital presenting with increases in bilateral pleural effusions and pericardial effusion. Repeated t...

journal_title：Clinical nephrology

authors： Iyoda M,Ajiro Y,Sato K,Kuroki A,Shibata T,Kitazawa K,Sugisaki T

更新日期：2006-04-01 00:00:00

abstract：AIMS:No conventional phosphate binder is entirely satisfactory for the treatment of hyperphosphatemia in patients with end-stage renal disease (ESRD). Consequently, there is a need for new agents. One such agent is lanthanum carbonate (La). This large-scale study compares the safety of La with standard therapy (any app...

journal_title：Clinical nephrology

authors： Finn WF,SPD 405-307 Lanthanum Study Group.

更新日期：2006-03-01 00:00:00